Endocrine

Diabetes
  • ACCORD. Effects of Intensive Glucose Lowering in Type 2 Diabetes. NEJM 2008; 358(24): 2545-59.
  • ACCORD. Long-Term Effects of Intensive Glucose Lowering on Cardiovascular Outcomes. NEJM 2012; 364(9): 818-28.
  • ACCORD. Effects of Intensive Blood-Pressure Control in Type 2 Diabetes. NEJM 2010; 362(17): 1575-85.
  • ACCORD. Effects of Combination Lipid Therapy in Type 2 Diabetes Mellitus. NEJM 2010; 362(17):1563-74.
  • ACCORD-Eye. Effects of Medical Therapies on Retinopathy Progression in Type 2 Diabetes. NEJM 2010; 363(3): 233-44.
  • ACCORD-Eye. Effect of Intensive Treatment of Hyperglycemia on Microvascular Outcomes in Type 2 Diabetes: an Analysis of the ACCORD Randomised Trial. Lancet 2010; 376: 419-430.
  • ACCORD. Action to Control Cardiovascular Risk in Diabetes (ACCORD) Trial: Design and Methods. Am J Cardiol 2007; 99: 21i-33i.
  • ADVANCE. Effects of a Fixed Combination of Perindopril and Indapamide on Macrovascular and Microvascular Outcomes in Patients with Type 2 Diabetes Mellitus: a Randomised Controlled Trial. Lancet 2007; 370: 829-40.
  • DPPRG. Reduction in the Incidence of Type 2 Diabetes Mellitus with Lifestyle Intervention or Metformin. NEJM 2002; 346(6): 393-403.
  • NICE-SUGAR. Intensive versus Conventional Glucose Control in Critically Ill Patients. NEJM 2009; 360(13): 1283-97.
  • RENAAL. Effects of Losartan on Renal and Cardiovascular Outcomes in Patients with Type 2 Diabetes and Nephropathy. NEJM 2001; 345(12):861-9.
  • UKPDS. Association of Systolic Blood Pressure with Macrovascular and Microvascular Complications of Type 2 Diabetes  (UKPDS 36): Prospective Observational Study. BMJ 2000; 321: 412-9.
Osteoporosis
  • FIT. Effect of Alendronate on Risk of Fracture in Women with Low Bone Density. JAMA 1998; 280: 2077-82.
  • FLEX. Effects of Continuing or Stopping Alendronate After 5 Years of Treatment. JAMA 2006; 296: 2927-38.
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